Determination of 1α,25(OH)2-Vitamin D3 (Calcitriol) in Human Plasma using the AB SCIEX API 4000TM System
نویسنده
چکیده
The routine adoption of liquid chromatography-tandem mass spectrometry (LC/MS/MS) for clinical research is rapidly gaining momentum. In order to realize the full benefits of adopting LC/MS/MS for analytical measurement, the sample preparation procedure needs to be inexpensive and simple to implement. For challenging applications such as the quantitative measurement of low-level steroids, immunoassay-based technologies have demonstrated insufficient specificity, resulting in poor accuracy and precision. Therefore, there are considerable advantages to be gained by switching to LC/MS/MS as the technique of choice.
منابع مشابه
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تاریخ انتشار 2010